BIO BENCH
Human CRP antibody and antigen
Human CRP antibody and antigen
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=============================================================
Click here to read more : Technical note: IVD material – Antibody and Protein
=============================================================
Any question, please contact: hxinfo@helixarbio.com
BioBench developped a series of clinical-qualified materials for IVD companies, as well as for lifesciences research. These materials including antibody pairs and purified antigens.
C-reactive protein (CRP, or named: PTX1, Pentraxin 1) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via C1q.
CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes). It is a member of the pentraxin family of proteins. It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.
Related Products and Application Suggestion
|
Product type |
Product name |
Catalog No. |
Host |
Antibody type |
Clone number |
Antibody pairing* / Protein usage |
Advised IVD platform** |
|
Protein/Antigen |
Human CRP |
CP0042 |
293T stable cell line expressed |
\ |
N/A |
Positive control, protein standard, reference substance |
All |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 01 |
MAB0316 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
01 |
Capture Ab: clone 01 Detection Ab: clone 02 |
POCT |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 02 |
MAB0317 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
02 |
Capture Ab: clone 01 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 03 |
MAB0318 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
03 |
Capture Ab: clone 03 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 05 |
MAB0319 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
05 |
Capture Ab: clone 05 Detection Ab: clone 06 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 06 |
MAB0320 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
06 |
Capture Ab: clone 06 Detection Ab: clone 05 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 31 |
MAB0321 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
31 |
Capture Ab: clone 31 Detection Ab: clone 32 |
CLIA |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 32 |
MAB0322 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
32 |
Capture Ab: clone 31 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 33 |
MAB0323 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
33 |
Capture Ab: clone 33 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 81 |
MAB0324 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
81 |
Not necessary for LETIA. |
LETIA |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 82 |
MAB0325 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
82 |
Not necessary for LETIA. |
|
|
Note: * Please test the usage of antibody pairs according to your own assay/method/platform/reagent. The listed data were tested in-house by BioBench and only shown as advice. ** Adapted platforms were tested in-house by Bio Bench and only shown as advise. Different assay/method/platform/reagent may lead to different performance of the antibody and protein. |
|||||||
CRP Antibody pair suggestion, performance and application suggestion
|
Tested Platform / Method |
Coating Antibody |
Detection Antibody |
BioBench Comment on Test Result |
LOD / Sensitivity |
Antigen Linearity Range |
|
POCT |
Clone 01 |
Clone 02 |
**** |
≤ 0.3 mg/L |
0.5 – 200 mg/L |
|
Clone 03 |
Clone 02 |
*** |
≤ 0.3 mg/L |
0.5 – 200 mg/L |
|
|
Clone 05 |
Clone 06 |
**** |
≤ 0.5 mg/L |
0.7 – 200 mg/L |
|
|
CLIA |
Clone 31 |
Clone 32 |
**** |
≤ 0.05 mg/L |
0.1 – 200 mg/L |
|
Clone 33 |
Clone 32 |
*** |
|||
|
LETIA |
Clone 81 |
**** |
≤ 0.3 mg/L |
0.5 – 300 mg/L |
|
|
Clone 82 |
**** |
≤ 0.5 mg/L |
0.7 – 300 mg/L |
||
|
These results were tested in-house by BioBench with limited selection of assay/platform/method/instrument/reagents. Please test the performance in your lab to confirm the performance. |
|||||
Materials
Materials
Plastic cassette
Terms and Conditions
Terms and Conditions
Read before you make an order: Terms and Conditions
Care Instructions
Care Instructions
This product is for biotechnology/life science research use only, not for house hold or medical use. Please operate under lab protocol and wear protections, including but not limited to: glasses, lab gloves and lab coat.
Description
=============================================================
Click here to read more : Technical note: IVD material – Antibody and Protein
=============================================================
Any question, please contact: hxinfo@helixarbio.com
BioBench developped a series of clinical-qualified materials for IVD companies, as well as for lifesciences research. These materials including antibody pairs and purified antigens.
C-reactive protein (CRP, or named: PTX1, Pentraxin 1) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via C1q.
CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes). It is a member of the pentraxin family of proteins. It is not related to C-peptide (insulin) or protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified.
Related Products and Application Suggestion
|
Product type |
Product name |
Catalog No. |
Host |
Antibody type |
Clone number |
Antibody pairing* / Protein usage |
Advised IVD platform** |
|
Protein/Antigen |
Human CRP |
CP0042 |
293T stable cell line expressed |
\ |
N/A |
Positive control, protein standard, reference substance |
All |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 01 |
MAB0316 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
01 |
Capture Ab: clone 01 Detection Ab: clone 02 |
POCT |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 02 |
MAB0317 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
02 |
Capture Ab: clone 01 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 03 |
MAB0318 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
03 |
Capture Ab: clone 03 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 05 |
MAB0319 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
05 |
Capture Ab: clone 05 Detection Ab: clone 06 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 06 |
MAB0320 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
06 |
Capture Ab: clone 06 Detection Ab: clone 05 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 31 |
MAB0321 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
31 |
Capture Ab: clone 31 Detection Ab: clone 32 |
CLIA |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 32 |
MAB0322 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
32 |
Capture Ab: clone 31 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 33 |
MAB0323 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
33 |
Capture Ab: clone 33 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 81 |
MAB0324 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
81 |
Not necessary for LETIA. |
LETIA |
|
Monoclonal antibody |
Anti Human CRP, Mouse mAb, 82 |
MAB0325 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
82 |
Not necessary for LETIA. |
|
|
Note: * Please test the usage of antibody pairs according to your own assay/method/platform/reagent. The listed data were tested in-house by BioBench and only shown as advice. ** Adapted platforms were tested in-house by Bio Bench and only shown as advise. Different assay/method/platform/reagent may lead to different performance of the antibody and protein. |
|||||||
CRP Antibody pair suggestion, performance and application suggestion
|
Tested Platform / Method |
Coating Antibody |
Detection Antibody |
BioBench Comment on Test Result |
LOD / Sensitivity |
Antigen Linearity Range |
|
POCT |
Clone 01 |
Clone 02 |
**** |
≤ 0.3 mg/L |
0.5 – 200 mg/L |
|
Clone 03 |
Clone 02 |
*** |
≤ 0.3 mg/L |
0.5 – 200 mg/L |
|
|
Clone 05 |
Clone 06 |
**** |
≤ 0.5 mg/L |
0.7 – 200 mg/L |
|
|
CLIA |
Clone 31 |
Clone 32 |
**** |
≤ 0.05 mg/L |
0.1 – 200 mg/L |
|
Clone 33 |
Clone 32 |
*** |
|||
|
LETIA |
Clone 81 |
**** |
≤ 0.3 mg/L |
0.5 – 300 mg/L |
|
|
Clone 82 |
**** |
≤ 0.5 mg/L |
0.7 – 300 mg/L |
||
|
These results were tested in-house by BioBench with limited selection of assay/platform/method/instrument/reagents. Please test the performance in your lab to confirm the performance. |
|||||