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Human IL-6 antibody and protein - IVD material
Human IL-6 antibody and protein - IVD material
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=============================================================
Click here to read more : Technical note: IVD material – Antibody and Protein
=============================================================
Any question, please contact: hxinfo@helixarbio.com
BioBench developped a series of clinical-qualified materials for IVD companies, as well as for lifesciences research. These materials including antibody pairs and purified antigens.
Human IL-6 (or named: Interleukin-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2), is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene.
In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1 and its activation of IL-1ra and IL-10.
There is some early evidence that IL-6 can be used as an inflammatory marker for severe COVID-19 infection with poor prognosis, in the context of the wider coronavirus pandemic.
Related Products and Application Suggestion
|
Product type |
Product name |
Catalog No. |
Host |
Antibody type |
Clone number |
Antibody pairing / Protein usage |
IVD platform |
|
Protein/Antigen |
Human IL-6 protein |
CP0041 |
293T stable cell line expressed |
\ |
N/A |
Positive control, protein standard, reference substance |
All |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 01 |
MAB0310 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
01 |
Capture Ab: clone 01 Detection Ab: clone 02 |
POCT |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 02 |
MAB0311 |
Mouse hybridoma |
Monoclonal antibody, IgG2a |
02 |
Capture Ab: clone 01 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 31 |
MAB0312 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
31 |
Capture Ab: clone 31 Detection Ab: clone 32 |
CLIA |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 32 |
MAB0313 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
32 |
Capture Ab: clone 31, clone 33, clone 34 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 33 |
MAB0314 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
33 |
Capture Ab: clone 33 Detection Ab: clone 32, clone 34 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 34 |
MAB0315 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
34 |
Capture Ab: clone 34 - Detection Ab: clone 32 Capture Ab: clone 33 - Detection Ab: clone 34 |
IL-6 Antibody pair suggestion, performance and application suggestion
|
Tested Platform / Method |
Coating Antibody |
Detection Antibody |
BioBench Comment on Test Result |
LOD / Sensitivity |
Antigen Linearity Range |
|
POCT |
Clone 01 |
Clone 02 |
**** Good result |
≤ 5 pg/mL |
7 – 6,000 pg/mL |
|
CLIA |
Clone 31 |
Clone 32 |
*** Good sensitivity |
≤ 1.5 pg/mL |
2 – 5,000 pg/mL |
|
Clone 33 |
Clone 34 |
*** Good sensitivity |
|||
|
Clone 33 |
Clone 32 |
**** Good specificity |
|||
|
Clone 34 |
Clone 32 |
**** Low background |
|||
|
These results were tested in-house by BioBench with limited selection of assay/platform/method/instrument/reagents. Please test the performance in your lab to confirm the performance. |
|||||
Materials
Materials
Plastic cassette
Terms and Conditions
Terms and Conditions
Read before you make an order: Terms and Conditions
Care Instructions
Care Instructions
This product is for biotechnology/life science research use only, not for house hold or medical use. Please operate under lab protocol and wear protections, including but not limited to: glasses, lab gloves and lab coat.
Concentration
Concentration
Antibody Host
Concentration
View full details
Description
=============================================================
Click here to read more : Technical note: IVD material – Antibody and Protein
=============================================================
Any question, please contact: hxinfo@helixarbio.com
BioBench developped a series of clinical-qualified materials for IVD companies, as well as for lifesciences research. These materials including antibody pairs and purified antigens.
Human IL-6 (or named: Interleukin-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2), is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene.
In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1 and its activation of IL-1ra and IL-10.
There is some early evidence that IL-6 can be used as an inflammatory marker for severe COVID-19 infection with poor prognosis, in the context of the wider coronavirus pandemic.
Related Products and Application Suggestion
|
Product type |
Product name |
Catalog No. |
Host |
Antibody type |
Clone number |
Antibody pairing / Protein usage |
IVD platform |
|
Protein/Antigen |
Human IL-6 protein |
CP0041 |
293T stable cell line expressed |
\ |
N/A |
Positive control, protein standard, reference substance |
All |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 01 |
MAB0310 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
01 |
Capture Ab: clone 01 Detection Ab: clone 02 |
POCT |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 02 |
MAB0311 |
Mouse hybridoma |
Monoclonal antibody, IgG2a |
02 |
Capture Ab: clone 01 Detection Ab: clone 02 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 31 |
MAB0312 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
31 |
Capture Ab: clone 31 Detection Ab: clone 32 |
CLIA |
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 32 |
MAB0313 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
32 |
Capture Ab: clone 31, clone 33, clone 34 Detection Ab: clone 32 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 33 |
MAB0314 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
33 |
Capture Ab: clone 33 Detection Ab: clone 32, clone 34 |
|
|
Monoclonal antibody |
Anti Human IL-6, Mouse mAb, 34 |
MAB0315 |
Mouse hybridoma |
Monoclonal antibody, IgG1 |
34 |
Capture Ab: clone 34 - Detection Ab: clone 32 Capture Ab: clone 33 - Detection Ab: clone 34 |
IL-6 Antibody pair suggestion, performance and application suggestion
|
Tested Platform / Method |
Coating Antibody |
Detection Antibody |
BioBench Comment on Test Result |
LOD / Sensitivity |
Antigen Linearity Range |
|
POCT |
Clone 01 |
Clone 02 |
**** Good result |
≤ 5 pg/mL |
7 – 6,000 pg/mL |
|
CLIA |
Clone 31 |
Clone 32 |
*** Good sensitivity |
≤ 1.5 pg/mL |
2 – 5,000 pg/mL |
|
Clone 33 |
Clone 34 |
*** Good sensitivity |
|||
|
Clone 33 |
Clone 32 |
**** Good specificity |
|||
|
Clone 34 |
Clone 32 |
**** Low background |
|||
|
These results were tested in-house by BioBench with limited selection of assay/platform/method/instrument/reagents. Please test the performance in your lab to confirm the performance. |
|||||